英文名称:Propargyl-PEG1-acid
Propargyl-PEG1-COOH
3-Prop-2-ynoxypropanoic acid
分子式:C6H8O3
分子量:128.1
CAS NO: 55683-37-9
MDL number:MFCD10689189
纯度:95%
保存方法:-20°C避光,避湿
产品简介:
Propargyl-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains a single PEG unit to help improve solubility.
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Propargyl-PEG3-amine 932741-18-9
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Propargyl-PEG4-Maleimide 1609651-90-2 丙炔基PEG马来酰亚胺
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Propargyl-PEG4-NHS ester 1428629-70-2 丙炔基PEG琥珀酰亚胺酯
Propargyl-PEG5-NHS ester 1393330-40-9
Alkyne-PEG1-COOH,55683-37-9,Alkyne-PEG1-ACID
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