Name:Pentostatin
Synonyms:CI-825,Deoxycoformycin
CAS Number:53910-25-1
Formula:C11H16N4O4
M.w.:268.27
DMSO (mg/mL)Max Solubility:54
DMSO (mM)Max Solubility:201.29
Form:Free Base
SMILES:OCC1OC(CC1O)[N]2C=NC3=C2NC=NCC3O
ALogP:-1.965
Target:Adenosine Deaminase,DNA/RNA Synthesis
Pathway:Neuronal Signaling
Information:Pentostatin(CI-825,Deoxycoformycin) is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
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