Name:Calcipotriene
Synonyms:Calcipotriol, MC903
CAS Number:112965-21-6
Formula:C27H40O3
M.w.:412.6
DMSO (mg/mL)Max Solubility:82
DMSO (mM)Max Solubility:198.74
Form:free base
SMILES:CC(\C=C\C(O)C1CC1)C2CCC3/C(CCCC23C)=C/C=C\4CC(O)CC(O)C4=C
ALogP:4.679
Target:Vitamin
Pathway:Metabolism
Information:Calcipotriene (Calcipotriol, MC903) is a synthetic derivative of calcitriol, a form of vitamin D. It can induce differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and lead to normalization of epidermal growth. Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
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