Name:Tacrine hydrochloride hydrate
Synonyms:Tacrine, Tetrahydroaminacrine, Tetrahydroaminoacridine
CAS Number:206658-92-6
Formula:C13H14N2.xHCl.xH2O
M.w.:198.26(free bases)
DMSO (mg/mL)Max Solubility:50
DMSO (mM)Max Solubility:252.19
Form:hydrochloride hydrate
SMILES:NC1=C2C=CC=CC2=NC3=C1CCCC3
ALogP:4.258
Target:AChR,HNMT
Pathway:Neuronal Signaling
Information:Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.
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