Name:Rosmarinic acid
Synonyms:Rosemary acid
CAS Number:20283-92-5
Formula:C18H16O8
M.w.:360.31
DMSO (mg/mL)Max Solubility:72
DMSO (mM)Max Solubility:199.83
Form:free base
SMILES:OC(=O)C(CC1=CC=C(O)C(=C1)O)OC(=O)\C=C\C2=CC=C(O)C(=C2)O
ALogP:2.706
Target:Complement System,IκB/IKK
Pathway:NF-κB
Information:Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling.
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