生物活性：Maprotiline-d5 (hydrochloride) is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Maprotiline-d5 hydrochloride 相关抗体:
FOXO1A Antibody
Beclin 1 Antibody
Atg12 Antibody
ATG5 Antibody
Bmi1 Antibody
FOXO4 Antibody
FOXP3 Antibody
GABARAP Antibody
LAMP2 Antibody (YA713)
LAMP2a Antibody
Phospho-FOXO3a(Ser253) Antibody
APG5L Antibody
ATG10 Antibody (YA603)
ATG3 Antibody
ATG4A Antibody
ATG4C Antibody
ATG7 Antibody
FOXO1 Antibody (YA430)
FOXO3 Antibody
FOXP3 Antibody (YA759)
FTO Antibody
Phospho-FOXO3A (Ser253) Antibody
FOXO1 Antibody
ATG10 Antibody
Granulin Antibody (YA1162)
ATG13 Antibody (YA1650)
ATG9A Antibody (YA3081)
LAMP2 Antibody (YA310)
WIPI1 Antibody (YA1721)
ATG16L1 Antibody (YA2187)
分子量：318.90
Formula：C20H19D5ClN
CAS 号：1794942-12-3
非标记 CAS：10347-81-6
中文名称：盐酸马普替林 d5 (盐酸盐)
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (527 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8.
 [Content Brief]
[3]. http://en.wikipedia.org/wiki/Maprotiline