生物活性：Axitinib-13C,d3 is a 13C-labeled and deuterium labeled Axitinib. Axitinib is a multi-targeted tyrosine kinase inhibitor with IC50 values of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1, VEGFR2, VEGFR3 and PDGFRβ, respectively[1][2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Axitinib-13C,d3 相关抗体:
Phospho-PDGFR beta (Y740) Antibody
VEGF Receptor 2 Antibody (YA014)
PDGFR alpha Antibody
VEGF Receptor 1 Antibody
VEGFA Antibody
VEGF Receptor2 Antibody
PDGF B Antibody (YA1556)
PLGF Antibody (YA1812)
PDGFR beta Antibody (YA1925)
VEGFD Antibody (YA2385)
Phospho-PDGFR beta (Tyr740) Antibody (YA3062)
PGF Antibody (YA1434)
Neuropilin 1 Antibody (YA1831)
VEGFB Antibody (YA2627)
分子量：390.48
Formula：C2113CH15D3N4OS
CAS 号：1261432-00-1
非标记 CAS：319460-85-0
性状：固体
颜色：White to off-white
中文名称：阿昔替尼 13C，d3
运输条件：Shipping with dry ice.
储存方式：-80°C