生物活性：Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM.
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Fenofibric acid-d6 相关抗体:
PPAR alpha Antibody
COX2 Antibody
PPAR gamma Antibody
COX IV Antibody
COX2/Cyclooxygenase 2 Antibody
PPAR gamma Antibody (YA122)
COX IV Antibody (YA867)
Cyclooxygenase 1 Antibody (YA2537)
Cyclooxygenase 2 Antibody (YA2541)
PGC1 beta Antibody (YA1411)
分子量：324.79
Formula：C17H9D6ClO4
CAS 号：1092484-69-9
非标记 CAS：42017-89-0
性状：固体
颜色：White to off-white
中文名称：非诺贝特酸 d6
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month