生物活性：Lidocaine-d10 is the deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia[2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Lidocaine-d10 相关抗体:
MEK1/2 Antibody
ERK1/2 Antibody
Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Antibody
NF-KB p65 Antibody
Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Antibody (YA455)
Phospho-NF-KB p65 (Ser536) Antibody
E-Cadherin Antibody (YA470)
Fatty Acid Synthase Antibody (YA766)
DYKDDDDK Tag (FLAG) Antibody
GAPDH Antibody
GFP Antibody
p53 Antibody (YA250)
RUNX2 Antibody
Phospho-NF-κB p65 (Ser529) Antibody
Ferritin Heavy Chain Antibody
COX2 Antibody
Ctip2 Antibody
Cyclin D1 Antibody (YA485)
Cytochrome C Antibody
NF-KB p65 Antibody (YA267)
ERK2 Antibody
c-Myc Antibody
Cyclin E1 Antibody
Phospho-MEK1 (Ser298) Antibody
xCT Antibody (YA006)
AIF Antibody (YA636)
ALIX Antibody
CNPase Antibody
Cortactin Antibody
COX IV Antibody
分子量：244.40
Formula：C14H12D10N2O
CAS 号：851528-09-1
非标记 CAS：73-78-9
性状：固体
颜色：Off-white to light yellow
中文名称：利多卡因 d10
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month