生物活性：Amodiaquine-d10 is the deuterium labeled Amodiaquine. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4].
IC50 & Target：Plasmodium
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Amodiaquine-d10 相关抗体:
Phospho-Histone H2A.X (Ser139) Antibody
Histone H3 (acetyl K27) Antibody
Phospho-Histone H2A.X (Ser139) Antibody (YA190)
TriMethyl-Histone H3 (Lys27) Antibody
Histone H2A(acetyl K9) Antibody
Histone H2A.X Antibody (YA380)
Histone H2B Antibody
Histone H3 Antibody
Histone H3 (acetyl K14) Antibody
Histone H3 (acetyl K18) Antibody
Histone H3 (acetyl K56) Antibody
Histone H3 (tri methyl K9) Antibody
Histone H3.3 Antibody
Histone H4 Antibody
Histone H4 (acetyl K16) Antibody
Histone H4 (acetyl K8) Antibody
Histone H4 (acetyl K5) Antibody
SUZ12 Antibody
WDR5 Antibody (YA008)
KMT6/EZH2 Antibody
Fibrillarin Antibody
Phospho-Histone H2A.X (Ser139) Antibody (YA191)
PRMT1 Antibody (YA686)
PRMT6 Antibody (YA685)
WDR77 Antibody (YA655)
PRMT3 Antibody (YA1731)
PRMT5 Antibody (YA1853)
EHMT2 Antibody (YA2373)
CBX4 Antibody (YA2490)
GGT1 Antibody (YA2634)
分子量：365.92
Formula：C20H12D10ClN3O
CAS 号：1189449-70-4
非标记 CAS：86-42-0
性状：固体
颜色：White to off-white
中文名称：阿莫地喹-d10
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month