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Alogliptin-d3,阿格列汀-d3; SYR-322-d3 free base「同位素标记抑制剂」

作者:瑞禧生物 发布时间:2025-06-10 09:38:16 次浏览

生物活性:Alogliptin-d3 is the deuterium labeled Alogliptin. Alogliptin (SYR-322 free base) is a potent, selective and orally active inhibitor of DPP-4 with an IC50 of <10 nM, and exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin can be used for the research of type 2 diabetes[1][2][3].
IC50 & Target:DPP-4
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Alogliptin-d3 相关抗体:
Ferritin Heavy Chain Antibody
AMID/FSP1 Antibody
Peroxiredoxin 1 Antibody (YA692)
PRDX3 Antibody (YA909)
Ferritin Light Chain Antibody (YA971)
Ferritin Light Chain Antibody (YA972)
DPP4/CD26 Antibody (YA1274)
分子量:342.41
Formula:C18H18D3N5O2
CAS 号:1133421-35-8
非标记 CAS:850649-61-5
性状:固体
颜色:White to off-white
中文名称:阿格列汀杂质30-d3
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years,4°C:2 years
In solvent:-80°C:6 months,-20°C:1 month