生物活性：(Rac)-Levomepromazine-d3 (hydrochloride) is a labelled racemic Methotrimeprazine, which is a phenothiazine which has antagonist actions at multiple neurotransmitter receptor sites, including dopaminergic, cholinergic, serotonin and histamine receptors[1][2].
IC50 & Target：D3 Receptor
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
(Rac)-Levomepromazine-d3 hydrochloride 相关抗体:
ADGRE1 (F4/80) Antibody (YA002)
ADGRE1 (F4/80) Antibody (YA920)
DRD2 Antibody
Dopamine Receptor D3 Antibody (YA1742)
DOPA Decarboxylase Antibody (YA2428)
Dopamine Receptor D1 Antibody (YA3270)
Torsin 1A Antibody (YA2935)
PITX3 Antibody (YA2974)
HMBS Antibody (YA3061)
分子量：367.95
Formula：C19H22D3ClN2OS
CAS 号：1216745-60-6
非标记 CAS：4185-80-2
性状：油状物
颜色：White to light yellow
中文名称：(±)-左美丙嗪-d6-d3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：-20°C, stored under nitrogen, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
纯度 & 产品资料
纯度： ≥97.0%
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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