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(Rac-Bedaquiline-d6,贝达喹啉-d6「同位素标记抑制剂」

作者:瑞禧生物 发布时间:2025-06-09 16:25:39 次浏览

生物活性:(Rac)-Bedaquiline-d6 is the deuterium labeled Bedaquiline (HY-14881)[1]. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit[2]. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis[3].
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
(Rac)-Bedaquiline-d6 相关抗体:
MRP2 Antibody
Elongation factor 2 Antibody (YA962)
Elongation factor 2 Antibody (YA964)
PU.1/SPI1 Antibody (YA1116)
Sulfadimidine Antibody (YA906)
Elongation factor 2 Antibody (YA963)
Anthrax Protective gen Antibody (YA1060)
Elongation factor 1 gamma Antibody (YA2004)
Pulmonary Surfactant Associated Protein D Antibody (YA2107)
Cathelicidin Antibody (YA2380)
Elongation Factor Ts Antibody (YA2524)
Elongation Factor 1A2 Antibody (YA2879)
BPI Antibody (YA3068)
MetRS Antibody (YA3196)
分子量:561.54
Formula:C32H25D6BrN2O2
CAS 号:2517573-53-2
非标记 CAS:843663-66-1
性状:固体
颜色:White to off-white
中文名称:(Rac)-贝达喹啉-d6
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years
In solvent:-80°C:6 months,-20°C:1 month