生物活性:Irinotecan-d10 (hydrochloride) is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1][2].
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
瑞禧生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Irinotecan-d10 hydrochloride 相关抗体:
TOP2A Antibody
DXd Antibody (YA897)
SN38 Antibody (YA923)
Topoisomerase I Antibody (YA2237)
分子量:633.20
Formula:C33H29D10ClN4O6
CAS 号:718612-62-5
非标记 CAS:100286-90-6
性状:固体
颜色:White to yellow
中文名称:伊立替康 d10 (盐酸盐)
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:4°C, sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)