瑞禧生物货号：Ruixi-B398155
化学名称：(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis-1-pyrrolidinecarboxylic Acid 1,1'-Bis(1,1-dimethylethyl) Ester
CAS号：1007882-23-6
分子式：C₃₆H₄₄N₆O₄
Appearance:White to Off-White Solid
Melting Point:213°C
分子量：624.77
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
产品应用：(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis-1-pyrrolidinecarboxylic Acid 1,1'-Bis(1,1-dimethylethyl) Ester is an antiviral agent and Daclatasvir (D101500) intermediate. Daclatasvir inhibits the HCV protein NS5A and thus can be used as a drug candidate for the treatment of hepatitis C (HCV).
参考文献：Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);
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