瑞禧生物货号：Ruixi-B394750
化学名称：N-Biotinylaminoethyl Methanethiosulfonate
同义名称：Methanesulfonothioic Acid S-[2-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl] Ester; MTSEA-BIOTIN;
CAS号：162758-04-5
分子式：C₁₃H₂₃N₃O₄S₃
Appearance:White to Off-White Solid
Melting Point:95-103°C
分子量：381.53
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Moisture Sensitive
产品类别：Research Tools; Cross-linkers; Sulfhydryl Active Reagents;
产品应用：Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. MTSEA-biotin has recently been used to probe the topology of the serotonin (5-HT) transporter by site-directed chemical labelling.
参考文献：J. Biol. Chem., 273(20), 12675 (1998), Adams, C.M., et al.: J. Biol. Chem., 273 (46), 30204 (1998), Boileau, A. J., et al.: J. Neurosci., 19, 12, 4847 (1999), Wagner, D.A.and Czajkowski, C.: J. Neurosci., 21, 67 (2001), Traebert, M.: J. Membr. Biol., 180, 83 (2001)
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