瑞禧生物货号：Ruixi-B207710
化学名称：Benzo[b]thien-2-yl Ketone (Zileuton Impurity)
同义名称：Bis(benzo[b]thien-2-yl)methanone; USP Zileuton Related Compound C;
CAS号：97978-07-9
分子式：C₁₇H₁₀OS₂
Appearance:Off-White to Pale Yellow Solid
Melting Point:161-166°C
分子量：294.39
Storage:-20°C, Light sensitive, Light sensitive
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
产品类别：Research Tools; Enzyme Activators and Inhibitors;
产品应用：Benzo[b]thien-2-yl ketone is an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that is used to treat patients with asthma. Benzo[b]thien-2-yl ketone is used as a reagent to synthesize Bis(1H-2-indolyl)methanone, compounds that inhibit the activity of growth factor receptor kinase. Benzo[b]thien-2-yl ketone is also used as a reagent to prepare annulated oligothiophenes, compounds that are used in organic light-emitting devides (OLEDs).
参考文献：Israel, E., et al.: JAMA, 275, 931 (1996); Mahboobi, S., et al.: J. Med. Chem., 45, 1002 (2002); Mitschke, U. & Bäuerle, P.: J. Chem. Soc. Perk. Trans., 1, 740 (2001); Nenajdenko, V., et al.: Russ. Chem. Bull., 61, 1456 (2012)
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