瑞禧生物货号:Ruixi-A628898
化学名称:[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester
同义名称:Phenyl Hydrogen [(R)-1-(6-Amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate;
CAS号:379270-35-6
分子式:C₁₅H₁₈N₅O₄P
Appearance:White to Off-White Solid
Melting Point:237-239°C
分子量:363.31
Storage:-20°C, Inert atmosphere
Solubility:Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
产品类别:Standards; Anti-virals/Anti-retrovirals;
产品应用:[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
参考文献:Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);
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