瑞禧生物货号：Ruixi-A628755
化学名称：2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
同义名称：2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone; (S)-1-(5-Fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propan-1-amine; (S)-2-(1-Aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;
CAS号：870281-86-0
分子式：C₁₇H₁₆FN₃O
Appearance:Off-White Solid
Melting Point:166-169ºC
分子量：297.33
Storage:4°C, Hygroscopic
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.
参考文献：Liu, J., et al.: Org. Prep. Proced. Int., 48, 337-341 (2016);
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