瑞禧生物货号：Ruixi-A627960
化学名称：Trelagliptin Trifluoroacetic Acid Salt
同义名称：2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile Trifluoroacetic Acid Salt
CAS号：928201-45-0
分子式：C₂₀H₂₁F₄N₅O₄
分子量：471.41
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluorobenzonitrile trifluoroacetic acid salt is a potent, selective, and noncovalent inhibitor of dipeptidyl peptidase IV (DPP-4). This inhibitor provides sustained reduction of plasma DPP-4 activity and lowering of blood glucose in animal models of diabetes.
参考文献：Augeri, D., et al.: J. Med. Chem., 48, 5025 (2005), Drucker, D., et al.: Lancet, 368, 1696 (2006), Cvetkovic, R., et al.: Drugs, 67, 935 (2007),
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