瑞禧生物货号:Ruixi-A601665
化学名称:N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester
同义名称:GS 7485;
CAS号:376633-26-0
分子式:C₁₅H₂₈N₇O₅P
Appearance:White to Off-White Solid
Melting Point:115 - 117°C
分子量:417.4
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
产品类别:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue
参考文献:Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),
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