瑞禧生物货号：Ruixi-A593985
化学名称：2-Amino-3-benzoyl-5-chloro-α-(propylthio)benzeneacetamide
同义名称：Nepafenac Impurity;
CAS号：1881270-48-9
分子式：C₁₈H₁₉ClN₂O₂S
分子量：362.87
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：2-Amino-3-benzoyl-5-chloro-α-(propylthio)benzeneacetamide is derived from Methyl Chloroacetate (M294960), which is widely used in the chemical and biochemical fields as an extraction solvent. Methyl chloroacetate is known to induce DNA damage to rat sperm, and is also thought to be toxic to humans upon exposure. Methyl chloroacetate is also used as a reagent to synthesize Valdecoxib (V090000), a selective cyclooxygenase 2(COX-2) specific inhibitor that is used to treat postoperative pain;Also, it is a non-steroidal anti-inflammatory drug (NSAID).
参考文献：Nussmeier, N., et al.: New Engl. J. Med., 352, 1081 (2005); Talley, J., et al.: J. Med. Chem., 43, 775 (2000); Wang, T., et al.: J. Chromatogr. A, 1147, 105 (2007); Wenye, L.: J. Anh. Agri. Sci., 35, 2581 (2007); Runje, M., et al.: J. Pharm. Biomed. Anal., 123, 42-52 (2016)
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