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CAS:924416-43-3|AdipoRon

作者:瑞禧生物 发布时间:2024-08-02 09:09:05 次浏览

瑞禧生物货号:Ruixi-A291670
化学名称:AdipoRon
同义名称:2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide; 2-(4-Benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide
CAS号:924416-43-3
分子式:C₂₇H₂₈N₂O₃
Appearance:White to Off-Whhite Solid
Melting Point:106-108°C
分子量:428.52
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
产品类别:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:AdipoRon is an AdipoR agonist and activates AMPK and PPAR-a pathways in the muscle and liver. AdipoRon ameliorated diabetes of genetically obese rodent model db/db mice, and prolonged the shortened lifespan of db/db mice on a high-fat diet. AdipoRon is a promising therapeutic approach for the treatment of obesity-related diseases such as type 2 diabetes.
参考文献:Okada-Iwabu, M., et. al.: Nature, 503, 493 (2013)
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