瑞禧生物货号:Ruixi-A291560
化学名称:Aderbasib
同义名称:(6S,7S)-7-[(Hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylic Acid Methyl Ester; INCB 007839;
CAS号:791828-58-5
分子式:C₂₁H₂₈N₄O₅
分子量:416.47
产品类别:Research Tools;
产品应用:Aderbasib is a azaspiro[2.5]octanehydroxamide derivative as inhibitor of metalloproteases for the treatment of disorders such as cancer, arthritis, cardiovascular or skin disorders.
参考文献:Kuipers, W., et al.: J. Med. Chem., 38, 1942 (1995), Molina, M.A., et al.: Clin. Cancer Res., 8, 347 (2002), Moss, M.L., et al.: Biochemistry, 43, 7227 (2004),
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