瑞禧生物货号：Ruixi-A247530
化学名称：Adefovir Dipivoxil Dimer
同义名称：Adefovir Dipivoxil Impurity B; 2,2-Dimethyl-propanoic Acid Methylenebis[imino-9H-purine-6,9-diyl-2,1-ethanediyloxymethylenephosphinylidynebis(oxymethylene)] Ester
CAS号：323201-05-4
分子式：C₄₁H₆₄N₁₀O₁₆P₂
Appearance:Clear Colorless Sticky Gel
Melting Point:No data available
分子量：1014.95
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：Adefovir Dipivoxil Dimer is a formed from the dimerization of Adefovir Dipivoxil (A280465) which is used as an oral reverse transcriptase inhibitor in the treatment of hepatitis B. Adefovir Dipivoxil Dimer’s presence indicates the degradation of Adefovir Dipivoxil under specific conditions suggesting the stability of Adefovir Dipivoxil is compromised under such conditions.
参考文献：Yuan, L., et al.: Pharm. Res., 17, 1098 (2000); Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010), Ming, X., et al.: Biochem. Pharmacol., 79, 455 (2010)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Delta is committed to providing cost-effective products that facilitate drug delivery with our customers.