瑞禧生物货号：Ruixi-A217325
化学名称：Adarotene
同义名称：(2E)​-3-​(4'-​Hydroxy-​3'-​tricyclo[3.3.1.13,​7]​dec-​1-​yl[1,​1'-​biphenyl]​-​4-​yl)​-​2-​propenoic Acid; (E)-3-(3'-((3r,5r,7r)-Adamantan-1-yl)-4'-hydroxy-[1,1'-biphenyl]-4-yl)acrylic Acid; ST 1926
CAS号：496868-77-0
分子式：C₂₅H₂₆O₃
分子量：374.47
产品类别：Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：Adarotene has been found to have antitumor activity against different types of cancer, including acute myeloid leukemia, primary effusion lymphoma, prostate cancer and glioma. It may also be useful in treating acute lung injury through inflammation and ROS suppression via inactivating TLR4​/NF-​κB and p38​/ERK1​/2 signaling pathways.
参考文献：El-Houjeiri, L., et al.: Mol. Cancer Ther., 16, 2047 (2017); Karam, L., et al.: Oncol. Rep., 39, 721 (2018); Bahmad, H. F., et al.: Mol. Carcinog., 58, 1208 (2019); De, L., et al.: Biomed. Pharmacother., 128, 110291 (2020); Dong, Z., et al.: Int. J. Mol. Med., 41, 3405 (2018)
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