瑞禧生物货号：Ruixi-A192220
化学名称：AC-93253 Iodide
同义名称：2-​[3-​(1,​3-​Dihydro-​1,​3,​3-​trimethyl-​2H-​indol-​2-​ylidene)​-​1-​propen-​1-​yl]​-​3-​ethylbenzothiazolium Iodide; 2-(3-(3-Ethylbenzo[d]thiazol-2(3H)-ylidene)prop-1-en-1-yl)-1,3,3-trimethyl-3H-indol-1-ium Iodide; 2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazoium Iodide; 3-Ethyl-2-((E)-3-((E)-1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)benzo[d]thiazol-3-ium Iodide
CAS号：108527-83-9
Alternate CAS #
61173-17-9
分子式：C₂₃H₂₅N₂S⁺ • I ⁻
分子量：361.53 + 126.91
产品类别：Standards; Molecular Biology; Enzyme Activators and Inhibitors; Dyes;
产品应用：AC-93253 Iodide is a RAR agonist. It is also a SIRT2 and Src inhibitor. It triggers the downregulation of melanoma progression markers and the inhibition of melanoma cell proliferation.
参考文献：Piu, F., et al.: Biochem. Pharmacol. (Amsterdam, Neth.), 71, 156 (2005); Zhang, Y., et al.: Biochem. Biophys. Res. Commun., 386, 729 (2009); Lai, Y., et al.: J. Hematol. Oncol., 10, 172/1 (2017); Karwaciak, I., et al.: Chem.-Biol. Interact., 236, 9 (2105)
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