Name:Fluorouracil (5-Fluorouracil, 5-FU)
Synonyms:NSC 19893,5-Fluorouracil, 5-FU
CAS Number:51-21-8
Formula:C4H3FN2O2
M.w.:130.08
DMSO (mg/mL)Max Solubility:26
DMSO (mM)Max Solubility:199.88
Form:free base
SMILES:FC1=CNC(=O)NC1=O
ALogP:-1.102
Target:Apoptosis related,DNA/RNA Synthesis,HIV,Nucleoside Analog/Antimetabolite,Thymidylate Synthase
Pathway:DNA Damage/DNA Repair
Information:Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.
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