Name:Desipramine Hydrochloride
Synonyms:Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901
CAS Number:58-28-6
Formula:C18H22N2.HCl
M.w.:302.84
DMSO (mg/mL)Max Solubility:60
DMSO (mM)Max Solubility:198.12
Form:hydrochloride
SMILES:Cl.CNCCCN1C2=C(CCC3=C1C=CC=C3)C=CC=C2
ALogP:4.234
Target:5-HT Receptor,Serotonin Transporter
Pathway:Neuronal Signaling
Information:Desipramine hydrochloride (Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901) is a dibenzazepine-derivative tricyclic antidepressant that acts as a selective norepinephrine reuptake inhibitor. It also shows weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects.
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