瑞禧生物货号:Ruixi-A187135
化学名称:5-[2-(Acetyloxy)ethyl]-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-2(3H)-thiazolethione
同义名称:[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-4-thiazoline-2-thione Acetate; 2-(3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-4-methyl-2-thioxo-2,3-dihydrothiazol-5-yl)ethyl acetate
CAS号:92325-11-6
分子式:C₁₄H₁₈N₄O₂S₂
Appearance:White Solid
分子量:338.45
Storage:-20°C
Solubility:Dichloromethane, DMSO, Methanol
产品类别:Standards; Enzyme Activators and Inhibitors; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:5-[2-(Acetyloxy)ethyl]-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-2(3H)-thiazolethione is an intermediate in synthesizing Thiothiamine (T375250), an impurity of Thiamine (T344185). Thiothiamine inhibits the activity of glutamate decarboxylase and decreases the concentration of GABA in brain tissue. Thiamine Impurity A.
参考文献:Koval'chuk, V.G. et al.: Tezisy Dokl.- Konf. Beloruss. Biokhim. O-va., 2, 135 (1974); Ostrovskii, Y. et al.: Biokhimiya, 34, 488 (1969)
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