瑞禧生物货号：Ruixi-A180180
化学名称：1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
同义名称：Apixaban Impurity;
CAS号：1801881-15-1
分子式：C₁₁H₁₁ClN₂O
分子量：222.67
产品类别：Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
产品应用：1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
参考文献：Luettgen, J. M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y. C., et al.: Thromb. Haemos., 105, 181 (2011);
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