瑞禧生物货号:Ruixi-A173633
化学名称:6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione
同义名称:Palbociclib Impurity;
Impurity:Palbociclib Impurity;
CAS号:2172256-78-7
分子式:C₁₅H₁₇N₃O₃
Appearance:Light Beige to Brown Solid
Melting Point:>201°C (dec.)
分子量:287.31
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
产品类别:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:6-Acetyl-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer.
参考文献:Finn, R., et al.: Breast Cancer Res., 11, 5 (2009);
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