瑞禧生物货号：Ruixi-D288115
化学名称：3-Desaminosulfonyl 2-Aminosulfonyl N-Acetyl Dorzolamide
同义名称：(4S,6S)-4-(Acetylethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonyl Chloride 7,7-Dioxide;
CAS号：403848-30-6
分子式：C₁₂H₁₆ClNO₅S₃
分子量：385.91
产品类别：Building Blocks; Miscellaneous;
产品应用：3-Desaminosulfonyl 2-Aminosulfonyl N-Acetyl Dorzolamide is an intermediate used in the synthesis of 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide (D288235), which is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100).
参考文献：Blacklock, T., et al.: J. Org. Chem., 58, 1672 (1993); Tempkin, O., et al.: Tetrahedron: Asym., 7, 2721 (1996)
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