瑞禧生物货号:Ruixi-D288060
化学名称:Depyrazine 7-Nitro-8-aminophenyl N-Trifluoroacetyl Varenicline
同义名称:1-(7-Amino-1,2,4,5-tetrahydro-8-nitro-1,5-methano-3H-3-benzazepin-3-yl)-2,2,2-trifluoroethanone
CAS号:950781-89-2
分子式:C₁₃H₁₂F₃N₃O₃
分子量:315.25
产品类别:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用:Depyrazine 7-Nitro-8-aminophenyl N-Trifluoroacetyl Varenicline is an impurity of Varenicline (V098490), a nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation.
参考文献:Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),
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