瑞禧生物货号：Ruixi-C240800
化学名称：Ivosidenib Isonicotinamide
同义名称：2-((S)-2-(((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)(5-fluoropyridin-3-yl)carbamoyl)-5-oxopyrrolidin-1-yl)isonicotinamide
CAS号：2408269-64-5
分子式：C₂₈H₂₄ClF₃N₆O₄
分子量：600.98
产品类别：Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
产品应用：Ivosidenib 5-Oxopyrrolidin-1-yl Isonicotinamide is a derivative of Ivosidenib (I940940(P)), which is a first-in-class mutant IDH1 inhibitor for the treatment of IDH1 mutant cancers.
参考文献：Popovici-Muller, J., et al.: ACS Medicinal Chemistry Letters, 9, 300 (2018);
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