5-TAMRA Picolyl Azide,Alexa Fluor 546
产品介绍
5-TAMRA Picolyl Azide
5-TAMRA Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concen*ration of Cu(I) at the reaction site. The chelating effect of picolyl azide moiety to raise the effective concen*ration of copper at the reaction site is so great that it leads to an increase of signal intensity of up to 40-fold. In addition, the use of 5-TAMRA Picolyl Azide instead of conventional 5-TAMRA Azide allows for at least a tenfold reduction in the concen*ration of the copper catalyst without sacrificing the efficiency of labeling.
Although the mixed isomers of 5(6)-TAMRA is a preferred, routinely used red fluorescent dye for staining proteins, labeling peptides and nucleotides with TAMRA mixed isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often reuired in the conjugation processes.
In summary, the in*roduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This will be of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
Abs/Em Maxima

545/576
Extinction coefficient

91,000
Flow cytometry laser line

532 or 555 nm
Microscopy laser line

532 or 555 nm
Spectrally similar dyes

Alexa Fluor® 546, Atto™ 543, CF™ 555 Dye, DyLight™549
Molecular weight

808.89
CAS

N/A
Solubility

DMSO, DMF, MeOH
Purity

>97% (HPLC)
Appearance

Red solid
Storage conditions

-20C
Shipping conditions

Ambient temperature
5-TAMRA Picolyl Azide,Alexa Fluor 546
西安瑞禧生物科技有限公司
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炔烃 Dye alkynes
1-Ethynyl pyrene
3-Ethynyl perylene
BDP FL alkyne
FAM alkyne, 5-isomer
FAM alkyne, 6-isomer
TAMRA alkyne, 5-isomer
BDP TMR alkyne
Cyanine3 alkyne
Cyanine5 alkyne
Cyanine5.5 alkyne
Cyanine7 alkyne
Cyanine7.5 alkyne
Sulfo-Cyanine3 alkyne
Sulfo-Cyanine5 alkyne
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西安瑞禧生物科技有限公司是国内一家生物科技公司，我公司专注于生产销售科研级别的药物传递和药物纳米靶向方面的产品，公司一直致力于研发纳米靶向科研产品以满足国内广大科研院校及其他相关科研单位的需求，公司目前经营的产品主要有合成磷脂，PEG衍生物，嵌段共聚物，纳米金，磁性纳米颗粒，介孔二氧化硅，活性荧光染料，荧光量子点，点击化学和大环配体等等，这些产品在国内给数家高校实验室和数十家中科研研究所及药厂长期供应，公司成立之初以代理国外进口品牌的为主，产品主要涉及磷脂、PEG衍生物等产品，随着公司的发展和扩大，公司更注重自主品牌的建立和产品研发并且注册了自己品牌商标，目前公司在销的90%的产品均为自主研发的Ruixibio®品牌产品，在未来3-5年公司预计将建立一个综合型的大型实验室，该实验室不仅提供纳米靶向药物科研产品及定制外包服务，还将承接其他研究领域的科研产品和定制外包服务。