Tetrazines demonstrate exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In addition, inverse-Electron-Demand Diels-Alder reaction of tetrazines trans-cyclooctenea forms a stable covalent bond and does not reuire Cu-catalyst or elevated temperatures. In applications such as in vivo cancer imaging or pre‐targeted cell labeling studies where rapid reaction kinetics are desired, a faster hydrogen substituted Cy®3 Tetrazine probe would be a probe of choice.
Cy®3 is a bright, water-soluble, and pH insensitive orange-fluorescent dye that can be excited using the 532 nm or 555 nm laser line and visualized with TRITC (tetramethylrhodamine) filter sets. Cy3 conjugates give less background than TAMRA and most other monly used fluorescent dyes.
Cy®Dye is a trademark of GE Healthcare.
Abs/Em Maxima
550/570 nm
Extinction coefficient
150,000
Flow cytometry laser line
532 or 555 nm
Microscopy laser line
532 or 555 nm
Spectrally similar dyes
Alexa Fluor® 555, Atto™ 555, CF™ 555 Dye, DyLight™555
Molecular weight
894.05
CAS
N/A
Solubility
Water, DMSO, DMF
Purity
>90% (HPLC)
Appearance
Red solid
Storage conditions
-20C
Shipping conditions
Ambient temperature
Cy3 Tetrazine|Cyanine3 tetrazine
Cyanine3 tetrazine, 1 mg
Cyanine3 tetrazine, 5 mg
Cyanine3 tetrazine, 25 mg
Cyanine3 tetrazine, 50 mg
Cyanine3 tetrazine, 100 mg
Cyanine3.5 azide, 100 uL, 10 mM/DMSO
Cyanine3.5 azide, 500 uL, 10 mM/DMSO
Cyanine3.5 azide, 1 mL, 10 mM/DMSO
Cyanine3.5 azide, 1 mg
Cyanine3.5 azide, 5 mg
Cyanine3.5 azide, 10 mg
Cyanine3.5 azide, 25 mg
Cyanine3.5 azide, 50 mg
Cyanine3.5 carboxylic acid, 1 mg
Cyanine3.5 carboxylic acid, 5 mg
Cyanine3.5 carboxylic acid, 25 mg
Cyanine3.5 carboxylic acid, 50 mg
Cyanine3.5 carboxylic acid, 100 mg
Cyanine3.5 NHS ester, 1 mg
Cyanine3.5 NHS ester, 5 mg
Cyanine3.5 NHS ester, 25 mg
Cyanine3.5 NHS ester, 50 mg
Cyanine3.5 NHS ester, 100 mg
Cyanine5 alkyne, 1 mg
Cyanine5 alkyne, 5 mg
Cyanine5 alkyne, 10 mg
Cyanine5 alkyne, 25 mg
Cyanine5 alkyne, 50 mg
Cyanine5 alkyne, 100 mg
Cyanine5 amine, 1 mg
Cyanine5 amine, 5 mg
Cyanine5 amine, 25 mg
Cyanine5 amine, 50 mg
Cyanine5 amine, 100 mg
Cyanine5 azide, 100 uL, 10 mM/DMSO
Cyanine5 azide, 500 uL, 10 mM/DMSO
Cyanine5 azide, 1 mL, 10 mM/DMSO
Cyanine5 azide, 1 mg
Cyanine5 azide, 5 mg
Cyanine5 azide, 10 mg
Cyanine5 azide, 25 mg
Cyanine5 azide, 50 mg
Cyanine5 azide, 100 mg
Cyanine5 Boc-hydrazide, 1 mg
Cyanine5 Boc-hydrazide, 5 mg
Cyanine5 Boc-hydrazide, 25 mg
Cyanine5 Boc-hydrazide, 50 mg
Cyanine5 Boc-hydrazide, 100 mg
Cyanine5 carboxylic acid, 1 mg
Cyanine5 carboxylic acid, 5 mg
Cyanine5 carboxylic acid, 25 mg
Cyanine5 carboxylic acid, 50 mg
Cyanine5 carboxylic acid, 100 mg
Cyanine5 DBCO, 1 mg
Cyanine5 DBCO, 5 mg
Cyanine5 DBCO, 10 mg
Cyanine5 DBCO, 25 mg
Cyanine5 DBCO, 50 mg
Cyanine5 DBCO, 100 mg
Cyanine5 hydrazide, 1 mg
Cyanine5 hydrazide, 5 mg
Cyanine5 hydrazide, 25 mg
Cyanine5 hydrazide, 50 mg
Cyanine5 hydrazide, 100 mg
Cyanine5 maleimide, 1 mg
Cyanine5 maleimide, 5 mg
Cyanine5 maleimide, 25 mg
Cyanine5 maleimide, 50 mg
Cyanine5 maleimide, 100 mg
Cyanine5 NHS ester, 1 mg
Cyanine5 NHS ester, 5 mg
Cyanine5 NHS ester, 25 mg
Cyanine5 NHS ester, 50 mg
Cyanine5 NHS ester, 100 mg
Cyanine5 NHS ester minimal dye, 5 nmol
Cyanine5 NHS ester minimal dye, 10 nmol
Cyanine5 NHS ester minimal dye, 25 nmol
Cyanine5 tetrazine, 1 mg
Cyanine5 tetrazine, 5 mg
Cyanine5 tetrazine, 25 mg
Cyanine5 tetrazine, 50 mg
Cyanine5 tetrazine, 100 mg
Cyanine5.5 alkyne, 1 mg
Cyanine5.5 alkyne, 5 mg
Cyanine5.5 alkyne, 10 mg
Cyanine5.5 alkyne, 25 mg
Cyanine5.5 alkyne, 50 mg
Cyanine5.5 alkyne, 100 mg
Cyanine5.5 amine, 1 mg
Cyanine5.5 amine, 5 mg
Cyanine5.5 amine, 25 mg
Cyanine5.5 amine, 50 mg
Cyanine5.5 amine, 100 mg
Cyanine5.5 azide, 100 uL, 10 mM/DMSO
Cyanine5.5 azide, 500 uL, 10 mM/DMSO
Cyanine5.5 azide, 1 mL, 10 mM/DMSO
Cyanine5.5 azide, 1 mg
Cyanine5.5 azide, 5 mg
Cyanine5.5 azide, 10 mg
Cyanine5.5 azide, 25 mg
Cyanine5.5 azide, 50 mg
Cyanine5.5 carboxylic acid, 1 mg
Cyanine5.5 carboxylic acid, 5 mg
Cyanine5.5 carboxylic acid, 25 mg
Cyanine5.5 carboxylic acid, 50 mg
Cyanine5.5 carboxylic acid, 100 mg
Cyanine5.5 hydrazide, 1 mg
Cyanine5.5 hydrazide, 5 mg
Cyanine5.5 hydrazide, 25 mg
Cyanine5.5 hydrazide, 50 mg
Cyanine5.5 hydrazide, 100 mg
Cyanine5.5 maleimide, 1 mg
Cyanine5.5 maleimide, 5 mg
Cyanine5.5 maleimide, 25 mg
Cyanine5.5 maleimide, 50 mg
Cyanine5.5 maleimide, 100 mg
Cyanine5.5 NHS ester, 1 mg
Cyanine5.5 NHS ester, 5 mg
Cyanine5.5 NHS ester, 25 mg
Cyanine5.5 NHS ester, 50 mg
Cyanine5.5 NHS ester, 100 mg
Cyanine5.5 tetrazine, 1 mg
Cyanine5.5 tetrazine, 5 mg
Cyanine5.5 tetrazine, 25 mg
Cyanine5.5 tetrazine, 50 mg
Cyanine5.5 tetrazine, 100 mg
Cyanine7 alkyne, 1 mg
Cyanine7 alkyne, 5 mg
Cyanine7 alkyne, 10 mg
Cyanine7 alkyne, 25 mg
Cyanine7 alkyne, 50 mg
Cyanine7 alkyne, 100 mg
Cyanine7 amine, 1 mg
Cyanine7 amine, 5 mg
Cyanine7 amine, 25 mg
Cyanine7 amine, 50 mg
Cyanine7 amine, 100 mg
Cyanine7 azide, 100 uL, 10 mM/DMSO
Cyanine7 azide, 500 uL, 10 mM/DMSO
Cyanine7 azide, 1 mL, 10 mM/DMSO
Cyanine7 azide, 1 mg
Cyanine7 azide, 5 mg
Cyanine7 azide, 10 mg
Cyanine7 azide, 25 mg
Cyanine7 azide, 50 mg
Cyanine7 carboxylic acid, 1 mg
Cyanine7 carboxylic acid, 5 mg
Cyanine7 carboxylic acid, 25 mg
Cyanine7 carboxylic acid, 50 mg
Cyanine7 carboxylic acid, 100 mg
Cyanine7 DBCO, 1 mg
Cyanine7 DBCO, 5 mg
Cyanine7 DBCO, 10 mg
Cyanine7 DBCO, 25 mg
Cyanine7 DBCO, 50 mg
Cyanine7 DBCO, 100 mg
Cyanine7 dicarboxylic acid, 100 mg
Cyanine7 dicarboxylic acid, 1 mg
Cyanine7 dicarboxylic acid, 25 mg
Cyanine7 dicarboxylic acid, 50 mg
Cyanine7 dicarboxylic acid, 5 mg
Cyanine7 hydrazide, 1 mg
Cyanine7 hydrazide, 5 mg
Cyanine7 hydrazide, 25 mg
Cyanine7 hydrazide, 50 mg
Cyanine7 hydrazide, 100 mg
Cyanine7 maleimide, 1 mg
Cyanine7 maleimide, 5 mg
Cyanine7 maleimide, 25 mg
Cyanine7 maleimide, 50 mg
Cyanine7 maleimide, 100 mg
Cyanine7 NHS ester, 1 mg
Cyanine7 NHS ester, 5 mg
Cyanine7 NHS ester, 25 mg
Cyanine7 NHS ester, 50 mg
Cyanine7 NHS ester, 100 mg
Cyanine7 tetrazine, 1 mg
Cyanine7 tetrazine, 5 mg
Cyanine7 tetrazine, 25 mg
Cyanine7 tetrazine, 50 mg
Cyanine7 tetrazine, 100 mg
Cyanine7.5 alkyne, 1 mg
Cyanine7.5 alkyne, 5 mg
Cyanine7.5 alkyne, 10 mg
Cyanine7.5 alkyne, 25 mg
Cyanine7.5 alkyne, 50 mg
Cyanine7.5 alkyne, 100 mg
Cyanine7.5 amine, 1 mg
Cyanine7.5 amine, 5 mg
Cyanine7.5 amine, 10 mg
Cyanine7.5 amine, 25 mg
Cyanine7.5 amine, 50 mg
Cyanine7.5 amine, 100 mg
Cyanine7.5 azide, 100 uL, 10 mM/DMSO
Cyanine7.5 azide, 500 uL, 10 mM/DMSO
Cyanine7.5 azide, 1 mL, 10 mM in DMSO
Cyanine7.5 azide, 1 mg
Cyanine7.5 azide, 5 mg
Cyanine7.5 azide, 10 mg
Cyanine7.5 azide, 25 mg
Cyanine7.5 azide, 50 mg
Cyanine7.5 azide, 100 mg
Cyanine7.5 carboxylic acid, 1 mg
Cyanine7.5 carboxylic acid, 5 mg
Cyanine7.5 carboxylic acid, 25 mg
Cyanine7.5 carboxylic acid, 50 mg
Cyanine7.5 carboxylic acid, 100 mg
Cyanine7.5 hydrazide, 1 mg
Cyanine7.5 hydrazide, 5 mg
Cyanine7.5 hydrazide, 25 mg
Cyanine7.5 hydrazide, 50 mg
Cyanine7.5 hydrazide, 100 mg
Cyanine7.5 maleimide, 1 mg
Cyanine7.5 maleimide, 5 mg
Cyanine7.5 maleimide, 25 mg
Cyanine7.5 maleimide, 50 mg
Cyanine7.5 maleimide, 100 mg
Cyanine7.5 NHS ester, 1 mg
Cyanine7.5 NHS ester, 5 mg
Cyanine7.5 NHS ester, 25 mg
Cyanine7.5 NHS ester, 50 mg
Cyanine7.5 NHS ester, 100 mg
Cyanine7.5 tetrazine, 1 mg
Cyanine7.5 tetrazine, 5 mg
Cyanine7.5 tetrazine, 25 mg
Cyanine7.5 tetrazine, 50 mg
Cyanine7.5 tetrazine, 100 mg
DBCO NHS ester, 10 mg
DBCO NHS ester, 25 mg
DBCO NHS ester, 50 mg
DBCO NHS ester, 100 mg
DBCO NHS ester, 1 g
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