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1353016-71-3,DBCO-NHS ester,DBCO活性酯/琥珀酰亚胺酯

作者:瑞禧生物 发布时间:2022-09-30 15:16:28 次浏览

中文名称:DBCO-NHS
英文名称:Dibenzocyclooctyne-N-hydroxysuccinimidyl ester
英文别名:DBCO-NHS ester
2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;
2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;
CAS号:1353016-71-3
分子式:C23H18N2O5
分子量:402.39900
质量:402.12200
PSA:83.99000
LogP:2.32330
供应商:瑞禧生物
结构式:

Description:
DBCO (Dibenzocyclooctyne) is a cycloalkyne that can reacts with azides via strain-promoted 1,3-dipolar cycloaddition in aqueous solution, a bioorthogonal reaction also termed Cu-free click reaction. This reaction has excellent selectivity and biocompatibility, such that the complimentary reagents can form covalent bonds with richly functionalized biological systems. The Cu-free click reaction has been a powerful tool in catalyst-free bioconjugation. DBCO reagents posses fast kinetcs and stability in aqueous buffer and they can be used to label azide-modified biomolecules with high specificity and reactivity.
Physical Properties:
Yellow/pale-yellow solid or viscous liquid;
Soluble in DMSO or DMF;
Storage Conditions:
Store at -20 0C, desiccate. NHS tends to hydrolyze from moisture. Avoid frequent thaw and frozen.
Copper-free Click Chemistry产品列表:
DBCO-PEG4-NHS ester
DBCO-PEG4-4-Formylbenzoate
DBCO-Sulfo-NHS ester
DBCO-NHS ester
DBCO-Acid
DBCO-PEG4-Acid
DBCO-Amine
DBCO-PEG4-Amine
DBCO-Maleimide
DBCO-PEG4-Maleimide
Fluorescent Probes
DBCO-Sulfo-link-Biotin
DBCO-PEG12-Biotin Conjugate
DBCO-PEG4-Biotin
Diazo Biotin-DBCO
DBCO-S-S-PEG3-Biotin
DBCO-S-S-PEG3-Biotin
DBCO-PEG4-Phosphoramidite
DBCO-PEG4-Hydroxyl
DBCO-PEG4-4-Formylbenzoate
Tetrazine-DBCO
DBCO-PEG4-DBCO
TCO-PEG12-DBCO
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