Exendin-4 货号 规格 价格 WH0001-1 1mg 1500.00 WH0001-5 5mg 3200.00 WH0001-10 10mg 4700.00 Exendin-4的生物活性 Exendin-4(Exenatide), a 39 amino acid peptide, activates GLP-1 (glucagon-like peptide-1) receptors to increase intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptor. IC50 Value: Target: Glucagon Receptor Exendin-4 stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1(glucagon-like peptide-1) receptor-dependent mechanism. Exendin-4, the long-acting GLP-1 receptor agonist, is an incretin mimetic approved for type 2 diabetes mellitus treatment. Studies also demonstrated its neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. 化学信息 分子量：4186.57 分子式：C₁₈₄H₂₈₂N₅₀O₅₀S CAS号：141758-74-9 溶剂/溶解度：10 mM in DMSO, H2O: ≤ 1.23 mg/mL (Need ultrasonic and warming) 纯度：大于98% 储存温度 -20℃