Cyanine5 DBCO，Cy5-DBCO，Cyanine5-Dibenzocycolctyne
A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.
Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.
Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.
       
 
        
 
 
 
 
一般特性
Appearance:dark blue solid
Mass spec M+ increment:928.4
Molecular weight:929.03
Molecular formula:C53H59N4F6O2P
Solubility:good in DMF, DMSO, chlorinated organic solvents
Quality :NMR 1H, HPLC-MS (95%)
Storage conditions:Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
 
光学特性
Excitation maximum, nm:646
ε, L⋅mol−1⋅cm−1:250000
Emission maximum, nm:662
Fluorescence quantum yield:0.2
CF260:0.03
CF280:0.04
Cyanine5 DBCO，Cy5-DBCO，Cyanine5-Dibenzocycolctyne