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Cy3 hydrazide (non-sulfonated)

作者:Cy3 hydrazide (non-sulfonated) 发布时间:2022-09-23 14:30:52 次浏览

carbonyl-reactive dye
Cy3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.
Cyanine3 dyes have been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc.
Cy3 hydrazide can be used to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone deamination or oxidative stress, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.
References:[1]. Pan D, Qin H, Cooperman BS.  Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop. RNA. 2009 Feb;15(2):346-54.[2]. Tamarit J, de Hoogh A, Obis E, et al.  Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides. J Proteomics. 2012 Jun 27;75(12):3778-88.[3]. Kameyama A, Kaneda Y, Yamanaka H, et al.  Detection of oligosaccharides labeled with cyanine dyes using matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem. 2004 Aug 1;76(15):4537-42.

Cy3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.


Cyanine3 dyes have been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc.


Cy3 hydrazide can be used to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone deamination or oxidative stress, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.


References:
[1]. Pan D, Qin H, Cooperman BS.  Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop. RNA. 2009 Feb;15(2):346-54.
[2]. Tamarit J, de Hoogh A, Obis E, et al.  Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides. J Proteomics. 2012 Jun 27;75(12):3778-88.
[3]. Kameyama A, Kaneda Y, Yamanaka H, et al.  Detection of oligosaccharides labeled with cyanine dyes using matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem. 2004 Aug 1;76(15):4537-42.


Cas No.
N/A
SDF


别名
N/A

化学名
1-(6-hydrazinyl-6-oxohexyl)-3,3-dimethyl-2-((1E,3E)-3-(1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)-3H-indol-1-ium chloride hydrochloride

Canonical SMILES
CN1C2=CC=CC=C2C(C)(C)/C1=C\C=C\C3=[N+](CCCCCC(NN)=O)C4=CC=CC=C4C3(C)C.[Cl-].Cl

分子式
C30H40Cl2N4O

分子量
543.57

溶解度
≥ 54.4mg/mL in DMSO, ≥ 48.2 mg/mL in EtOH, ≥ 50.8 mg/mL in H2O
储存条件
Store at -20°C


General tips
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.


Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request