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BDP FL tetrazine

作者:BDP FL tetrazine 发布时间:2022-09-20 14:20:48 次浏览

瑞禧货号:R08-0003
Product Name: BDP FL tetrazine
Molecular Formula: C24H24N7BF2O
Molecular Weight: 475.3
Purity: NMR 1H, HPLC-MS (95%)
Solubility: good in DCM, DMSO, DMF
CAS Number: 2042193-77-9
Product Specification

Appearance: red crystalline solid
ε, L⋅mol-1⋅cm-1: 92000
Fluorescence quantum Yield: 0.97
Storage Conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
Excitation Maximum (nm): 503
Emission Maximum (nm): 509Inverse electron demand Diels-Alder reaction (ied-DA) with tetrazines is a promising tool for the conjugation of biomolecules. The reaction takes place between tetrazine as an electron acceptor heterodiene, and a strained dienophile, such as trans-cyclooctene, cyclopropene, or some cyclooctynes.Methyltetrazine provides greater stability in buffers than unsubstituted tetrazine. The rate of its reaction with cycloalkenes still beats almost all other conjugation reaction rates by a factor of magnitudes.