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Aminooxy-PEG2-bis-PEG3-DBCO

作者:Aminooxy-PEG2-bis-PEG3-DBCO 发布时间:2022-09-19 15:28:51 次浏览


Chemical Formula: C70H92N8O18
Molecular Weight: 1333.52
CAS: N/A
Purity: >90%
Physical Form: light yellow oil
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC
Aminooxy-PEG2-bis-PEG3-DBCO is a heterotrifunctional linker containing two DBCO moieties for click chemistry and a oxyamine foe oxime ligation. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
Hydrophilic PEG3 Spacer – reduces aggregation, minimizes steric hindrance, and enhances solubility