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DBCO-PFP

作者:DBCO-PFP 发布时间:2022-09-19 15:28:51 次浏览


Chemical Formula: C25H14F5NO3
Molecular Weight: 471.09
CAS: N/A
Purity: >95%
Physical Form: light yellow powder
Solubility: DCM, THF, acetonitrile, DMF and DMSO
Storage at: -20 oC
DBCO-PFP is a heterobifunctional linker containing a DBCO moiety for click chemistry and a PFP activated ester. The dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst.
Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst
High chemoselectivity – azides and DBCO groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency