DSPE-PEG-BIOTIN
作者:DSPE-PEG-BIOTIN 发布时间:2022-08-01 09:05:19
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DSPE-PEG-BIOTIN
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotin(polyethylene
glycol)]
Synonym: Biotin
PEG DSPE.
Product
Structure:
Product
Specifications:
l Catalog
Numbers:PS2-BNDE-1K,2K,3K,5K,10K.
l Appearance: White
to off-white solid.
l Solubility: >5
mg/mL in hot water, chloroform, DCM.
l Stability: 1 Years at-20°C, Desiccate.
l CAS
Number: 385437-57-0.
l Molecular
Weight(PEG):1K,2K,3.4K,5K,10K.
l Functional
group: Biotin.
l Reactive
to: Avidin or streptavidin.
l Purity: 95%.
Description:
DSPE PEG Biotin is one of
Nanocs’ functional phospholipid PEG derivatives that have a biotin and a DSPE
phospholipid bridged by a linear PEG linker. DSPE
(1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon phospholipid that
is highly hydrophobic. PEG backbone, on the other hand, offers good
hydrophilicity and water solubility. Biotin is a commonly used bioactive
molecule that has high binding affinity toward avidin or streptavidin.
Biotin/streptavidin system has been exploited extensively for protein, nucleic
acid and many other biomolecule detection and purification. Biotin modified DSPE PEG can be
incorporated into liposome and other nanoparticles and thus it can be used to
target and detect avidin or streptavidin conjugated substrates.
Handling
and Use:
DSPE
PEG Biotin should always be kept in low temperature in dry condition. Prepare fresh
solution right before use.Avoid frequent thaw and freezing. For more
information about using this product, .
Related
Products:
DSPE-PEG-NH2, DSPE-PEG-COOH
DSPE-PEG-NHS ,DSPE-PEG-FA
DSPE-PEG-SH,DSPE-PEG-MAL
References:
l Nano-biotinylated
liposome-based immunoassay for the ultrasensitive detection of protein
biomarker in urine------ Talanta(IF=4.916).
l A rapid
and efficient technique for liposomal and nonliposomal drug pharmacokinetics
studies using magnetic nanoprobes and its application to leakage kinetics of
liposomes------ Journal of Chromatography A(IF=3.716).
This
product is for research use only and is not intended for use in humans or for
diagnostic use.