Human IgG3-λ来源于人类骨髓瘤血浆； MDL number MFCD00163926 NACRES NA.46产品描述 General description Identity of IgG3, lambda light chain is verified by subclass monoclonal antibodies and type specific polyclonal antibodies in immunoelectrphoresis and indirect ELISA assays. IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections.[1] IgG3 is the has a unique extended hinge region conferring greater flexibility IgG3, λ from human myeloma plasma is purified by fractionation, ion-exchange and affinity chromatography. Mammalian immunoglobins contain either lambda or kappa light chains. IgG3，λ轻链的身份已通过亚类单克隆抗体和类型特异性多克隆抗体在免疫电泳和间接ELISA分析中得到验证。IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它由B细胞分泌，存在于血液和细胞外液中，可防止细菌，真菌和病毒引起的感染。母体IgG通过胎盘转移到胎儿，这对新生儿抵抗感染的免疫防御至关重要。IgG3具有独特的延伸铰链区，赋予更大的灵活性。通过分馏，离子交换和亲和色谱法纯化来自人骨髓瘤血浆的IgG3，λ。 哺乳动物免疫球蛋白含有λ或κ轻链。 Application IgG3, lambda light chain may be used as an antigen for the production and evaluation of antibodies developed for the indentification and classification of IgG3 subtypes. The purified IgG3, lambda may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays. The purified IgG3, λ may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays. λ3轻链IgG3可用作抗原，用于产生和评估为鉴定和分类IgG3亚型而开发的抗体。纯化的IgG3λ可以用作免疫球蛋白校准剂，参考抗原，封闭剂或包被蛋白，用于多种免疫测定中，包括ELISA，斑点印迹免疫结合，蛋白质免疫印迹，免疫扩散，免疫电泳，血凝和细胞结合测定。 纯化的IgG3，λ可以在多种免疫测定中用作免疫球蛋白校准物，参考抗原，封闭剂或包被蛋白，包括ELISA，斑点印迹免疫结合，Western免疫印迹，免疫扩散，免疫电泳，血凝和细胞结合测定。 Physical form Solution in 20 mM tris buffered saline, pH 8.0. Analysis Note The purity and identity are determined by immunoelectrophoresis, indirect ELISA, and SDS-PAGE. Disclaimer Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. 性质 Quality Level 200 biological source human antibody form purified immunoglobulin assay >90% (microfluidic capillary gel electrophoresis) conjugate unconjugated shipped in dry ice storage temp. −20°C 安全信息 RIDADR NONH for all modes of transport 闪点（华氏） Not applicable 闪点（摄氏） Not applicable