DSPE-PEG-Aldehyde,DSPE-PEG-CHO
作者:DSPE-PEG-Aldehyde,DSPE-PEG-CHO 发布时间:2022-07-27 14:58:02
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商品型号:R-ADDE-1K,2K,3K,5K,10K
英文简称:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[aldehyde(polyethylene glycol)]
分子量:1K,2K,3K,5K,10K
规格:500mg,1g
DSPE-PEG-Aldehyde,DSPE-PEG-CHO
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[aldehyde(polyethyleneglycol)]
Synonym: AldehydePEG DSPE, DSPE PEG CHO.
ProductStructure:
ProductSpecifications:
CatalogNumbers:PS2-ADDE-1K,2K,3K,5K,10K.
Appearance: Whiteto off-white solid.
Solubility: 10mg/mL in hot water, chloroform, DCM.
Stability: 6 months at-20°C, Desiccate.
CASNumber: -.
MolecularWeight(PEG):1K,2K,3.4K,5K,10K.
Reactivegroup: Aldehyde.
Purity: >90%.
Description:
DSPE-PEG-aldehyde is one of reactive phospholipid PEG derivatives that can react with N-terminusamine groups. DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18carbon phospholipid that is highly hydrophobic. PEG backbone, on the otherhand, offers good hydrophilicity. DSPE-PEG-aldehyde is a reactive lipid PEG with good reactivity towards amine, oxyamine orhydrazide groups. Aldehyde reacts with N-terminus amine groups to form an intermediateSchiff base. Further reduction with hydride will form a stable C-N bond. DSPE-PEG-aldehyde allows conjugation ofDSPE PEG to amine or hydrazide group at acidic conditions with goodselectivity. Higher pH will result in multiple pegylation with amine groups.
Handlingand Use:
DSPE-PEG-aldehyde should always be kept in low temperature indry condition. Prepare fresh solution right before use.Avoid frequent thaw andfreezing. For more information about using this product,
RelatedProducts:
DSPE-PEG-NH2,DSPE-PEG-COOH
DSPE-PEG-NHS,DSPE-PEG-FA
DSPE-PEG-SH,DSPE-PEG-MAL
Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.