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PEG衍生物 荧光标记 点击化学 磷脂类 小分子定制

IR-825,CAS:1558079-49-4

作者:瑞禧生物 发布时间:2022-11-22 15:16:20 次浏览

新吲哚菁绿染料IR-825,CAS:1558079-49-4
英文名:IR-825
3-[(4-Carboxyphenyl)methyl]-2-[2-[3-[2-[3-[(4-carboxyphenyl)methyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]ethylidene]-2-chloro-1-cyclohexen-1-yl]ethenyl]-1,1-dimethyl-1H-benz[e]indolium
产品名称:3-[(4-羧基)甲]-2-[2-[3-[2-[3-[(4-羧基基)甲基]-1,3-二氢-1,1-二甲-2H-苯并[e]吲哚-2-亚基]亚乙基]-2-氯-1-环己烯-1-基]乙烯基]-1,1-二甲-1H-苯并[e]吲哚鎓
CAS:1558079-49-4
分子式:C54H48ClN2O4
分子量:824.42
产品简介:
IR-825, after encapsulated into nanoparticles may be useful for cancer photothermal and photodynamic therapy. IR-825 nanoparticles showed pH-dependent fluorescence emission and excellent near-infrared (NIR) irradiation of cancer cells targeted in vitro to provide cytotoxicity. IR-825 nanoparticles showed efficient tumor homing together with rapid renal excretion behaviors, as revealed by MR imaging and confirmed by biodistribution measurement. Notably, when irradiated with an 808 nm laser, tumors on mice with IR-825 nanoparticle injection are compley eliminated without recurrence within 60 days, demonstrating the high efficacy of photothermal therapy.
新吲哚菁绿染料IR-825,CAS:1558079-49-4