欢迎访问西安瑞禧生物技术有限公司官方网站

图片名

全国订购热线:
18966759382

首页 > 新品推荐 > PEG衍生物

PEG衍生物
PEG衍生物 MOF材料 磁性纳米颗粒 功能性聚合物 磷脂 纳米金 嵌段共聚物

DBCO-PEG-MAL,二苯并环辛烯PEG马来酰亚胺

作者:瑞禧生物 发布时间:2023-02-07 09:35:11 次浏览

DBCO-PEG-MAL,二苯并环辛烯PEG马来酰亚胺,DBCO-PEG-Maleimide,产品瑞禧生物强势推出,自主研发,欢迎选购!
名称
货号
英文名、缩写
分子量
DBCO-PEG-MAL
PS2-MDB-5K
DBCO-PEG-MAL
5000
0.1g、0.5g
DBCO-PEG-MAL
PS2-MDB-2K
DBCO-PEG-MAL
2000
0.1g、0.5g
DBCO-PEG-MAL
PS2-MDB-3K
DBCO-PEG-MAL
3400
0.1g、0.5g
DBCO-PEG-MAL
PS2-MDB-1K
DBCO-PEG-MAL
1000
0.1g、0.5g
DBCO-PEG-MAL
PS2-MDB-10K
DBCO-PEG-MAL
10000
0.1g、0.5g
(备注:非常规分子量:400、600。精确聚合度的小分子定制。)
基本信息:
中文名称:二苯并环辛烯-聚乙二醇-马来酰亚胺 (DBCO-PEG-MAL)
别名:DBCO-PEG-Maleimide
英文名称:DBCO-PEG-Maleimide,DBCO-PEG-MAL
CAS:-
分子量:400、600、1K、2K、3.4K、4K、5K、10K
纯度:95%以上
DBCO-PEG-MAL,二苯并环辛烯PEG马来酰亚胺,DBCO-PEG-Maleimide,产品瑞禧生物强势推出,自主研发,欢迎选购!
应用简介:
Maleimide PEG DBCO (dibenzocycolctyne) is one of 瑞禧生物 DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Copper-free Click Reaction Procedures:
Prepare the azide-containing reagents in reaction buffer.
Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4℃.
Purify conjugates either by dialysis or size-exclusion chromatograph.
物理性质:
状态:淡黄色到黄色固体,或者半固体,取决于分子量。
溶解性:溶于DMSO,DMF等溶剂。
保持条件:-20℃*保存,避光,干燥。
注意事项:取用一定要干燥,避免频繁的溶解和冻干。
反应性:DBCO于含有N3基团的反应。MAL可以和SH。
,DBCO-PEG-Maleimide,产品瑞禧生物强势推出,自主研发,欢迎选购!
技术指标:
纯度(PEG):95%以上
取代率(DBCO):90%以上
取代率(MAL):90%以上
分散系数(PDI):小于等于1.05
分析:COA、GPC、NMR、MALDI-TOF
相关产品*:
MPEG-DBCO
DBCO-PEG-NH2
DBCO-PEG-COOH
DBCO-PEG-NHS
DBCO-PEG-SH
DBCO-PEG-ACRL
DBCO-PEG-ACA
DBCO-PEG-DSPE
DBCO-PEG-FITC
DBCO-PEG-RB
DBCO-PEG-MAL
DBCO-PEG-FA
DBCO-PEG-BIOTIN
DBCO-PEG-OH
DBCO-PEG-OPSS
LA-PEG-DBCO
4ARM-PEG-DBCO
,DBCO-PEG-Maleimide,产品瑞禧生物强势推出,自主研发,欢迎选购!